Solitary plasmacytoma of bone vs. extramedullary plasmacytoma and their relationship to multiple myeloma

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Solitary bone and extramedullary plasmacytoma.

Less than 5% of patients with a plasma cell dyscrasia present with a single bone (SBP) or extramedullary plasmacytoma (EMP) without evidence of systemic disease (normocalcemia, absence of anemia, preservation of uninvolved immunoglobulins, or renal disease attributable to myeloma). Diagnosis requires biopsy confirmation of a monoclonal plasma cell infiltrate from a single site. The treatment of...

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A Review for Solitary Plasmacytoma of Bone and Extramedullary Plasmacytoma

Solitary plasmacytoma (SP) is characterized by a mass of neoplastic monoclonal plasma cells in either bone (SBP) or soft tissue without evidence of systemic disease attributing to myeloma. Biopsy confirmation of a monoclonal plasma cell infiltration from a single site is required for diagnosis. The common presentation of SBP is in the axial skeleton, whereas the extramedullary plasmacytoma (EMP...

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A 60 years old male presented with chief complaints of gradually increasing painful swelling on the forehead in the midline for the period of one year. There was no other significant history. General examination revealed pallor. Regional examination revealed an approximately 6x6 cm sized, soft to firm, tender swelling over forehead in the midline extending superiorly upto the hairline and infer...

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Solitary plasmacytoma of bone and asymptomatic multiple myeloma.

There is a wide spectrum of disease among patients with plasma cell myeloma. A small fraction have a localized plasmacytoma of bone that requires specialized techniques for accurate staging, followed by local radiotherapy that may be curative in some patients. Other patients with multiple myeloma may be free of symptoms and the disease is recognized by chance laboratory studies. Some have a pro...

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ژورنال

عنوان ژورنال: Cancer

سال: 1979

ISSN: 0008-543X,1097-0142

DOI: 10.1002/1097-0142(197903)43:3<1007::aid-cncr2820430333>3.0.co;2-4